Cabaletta Bio
Remote (Eastern Time Hours)
Cabaletta Bio (Nasdaq: CABA) is a clinical-stage biotechnology company focused on developing and launching the first curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. Cabaletta Bio’s headquarters and labs are located in Philadelphia, PA. For more information, please visit www.cabalettabio.com and connect with us on LinkedIn.
Uniquely Differentiated. Rapid. Elegant.
At Cabaletta, we are driven by the mission of developing cures, where a patients’ own cells are used to fight disease. We are building a culture grounded in the knowledge that successful cures can be achieved for patients if every member of the Cabaletta is focused on the success of the team. To nurture this, we make an active commitment to the well-being and continuous growth of each employee who joins the team. In this way, we are not only working to improve the lives of patients, but of everyone involved. #CabalettaCrew.
We’re proud to be a Great Place to Work-Certified™ company! #GPTWcertified Check out what our employees say makes working here so great: Working at Cabaletta Bio Inc | Great Place to Work®
We are seeking a highly motivated and experienced Senior Director, Field Medical Affairs Team Lead to lead the strategic development, build-out, and execution of the field medical organization in support of rese-cel in myositis and other autoimmune diseases. This leader will play a critical role in shaping field medical strategy, generating scientific insights, and establishing strong relationships with trial investigators, key opinion leaders (KOLs) and cell therapy treatment centers in a highly specialized and evolving therapeutic area.
This position requires deep expertise in cell therapy, strong leadership capabilities, and experience in launching cellular therapies, including building teams, developing field strategies, and aligning cross-functional stakeholders.
Build, lead, and mentor a high-performing MSL team aligned with pre-launch and launch objectives
Establish team structure, hiring plans, onboarding, and training programs tailored to cell therapy complexities
Foster a culture of scientific excellence, compliance, collaboration, and continuous learning
Set performance expectations and ensure execution against strategic medical goals
Develop and implement the field medical strategy for rese-cel in alignment with medical and business plans
Translate clinical and scientific data into impactful field engagement strategies
Ensure readiness for launch, including scientific messaging, training materials, and KOL engagement plans
Lead insight generation and ensure actionable feedback is integrated into broader medical and commercial strategies
Oversee strategic engagement with KOLs, investigators, and key cell therapy treatment centers
Guide MSL team in delivering high-quality scientific exchange and managing complex clinical discussions
Support advisory boards, investigator meetings, and scientific forums (including medical conferences) as appropriate
Identify emerging thought leaders and key institutions in the cell therapy ecosystem
Partner closely with Clinical Development, Clinical Operations, Commercial, Market Access, and Compliance Teams in order to achieve company objectives for clinical trial execution and pre-launch planning.
Provide field insights to inform clinical trial design, evidence generation, and access strategies
Support pre-launch planning, including disease state education and treatment pathway mapping
Ensure alignment between field medical activities and broader organizational objectives
Participate in the development of launch readiness plans from a field medical affairs perspective
Anticipate and address barriers related to cell therapy adoption (e.g., site readiness, logistics, safety concerns)
Have an understanding of the national and regional healthcare and access environment
Contribute to scientific narrative development and publication strategy
Ensure compliance with all regulatory and legal requirements
Develop and manage budgets, KPIs, and reporting frameworks for the MSL organization
Implement systems and tools to optimize field medical effectiveness
